Resveratrol is a stress-relieving agent.
- May 24, 2022
- 2 min read
Resveratrol Gains A New Talent
A research team that is part of The Scripps Research Institute (TSRI) discovered a brand new target for resveratrol, as reported in the month of Dec (Nature, doi:10.1038). This Nature article is interesting because it further demonstrates how adaptable the best resveratrol supplement truly is.

Resveratrol Really Does It All
As the article reviews in its abstract about resveratrol, "resveratrol provides cardio-neuro-protective, anti-diabetic and anti-cancer effects". To have a substance with an array of diverse functions, it is obvious that it needs to have many cellular targets to respond in such a broadway.
Resveratrol Is Utilized in Stress Response
For instance, In 2012, researchers discovered that grape seed extract resveratrol specifically binds to and blocks the activities of enzymes known as PDE. (PDE) and is believed to regulate the key stress response proteins that contribute to the prevention of age-related metabolic diseases (for an overview of that article, please refer to the February issue of our Resveratrol Newsletter).
Greater Stress-Protection from Resveratrol
The TSRI research team discovered that resveratrol binds directly to an enzyme known as tRNA synthetase in the recently published paper. It is normally involved in the production of proteins. The most interesting part of this research is that when resveratrol was bound to tRNA synthetases, it directed the enzymes to trigger stress protein pathways. This is a totally new role of this enzyme. But, this study is similar to previous studies of resveratrol in the sense that resveratrol can activate stress-related responses, which could result in the protection of tissues and cells and prevent the onset of age-related illnesses, which can lead to prolongation of life. Additionally, they discovered an entirely new target in the cellular system for resveratrol; researchers discovered that the target was 1000 times stronger than the other targets of resveratrol. This was also a first and could help explain the apparent findings of many scientists that resveratrol affects different cells in different ways and at different levels. It could be that the stimulation of stress through synthetase of tRNA may be more relevant for certain cells than for others. This being said, it will be important to find out ways to maximize the advantages of resveratrol in a particular cell or tissue-specific way to slow the progression of age-related illnesses. In the meantime,, regardless of the goal and the level of stress pathway activation or sensitivity, keep taking super micronized resveratrol to reap its health advantages.


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